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1

Toxicokinetics of N-ethyl-2-pyrrolidone and its metabolites in blood, urine and amniotic fluid of rats after oral administration

Bury, Daniel, Saillenfait, Anne Marie, Marquet, Fabrice, Käfferlein, Heiko U., Brüning, Thomas, Koch, Holger M.

Journal:

Archives of Toxicology

Année:

2019

Langue:

english

Fichier:

PDF, 691 KB

english, 2019

2

Considerations for the design and technical setup of a human whole-body exposure chamber

Monsé, Christian, Sucker, Kirsten, van Thriel, Christoph, Broding, Horst Christoph, Jettkant, Birger, Berresheim, Hans, Wiethege, Thorsten, Käfferlein, Heiko, Merget, Rolf, Bünger, Jürgen, Brüning, Th

Journal:

Inhalation Toxicology

Année:

2012

Langue:

english

Fichier:

PDF, 861 KB

english, 2012

3

Analysis of inflammatory markers and metals in nasal lavage fluid of welders

Raulf, Monika, Weiss, Tobias, Lotz, Anne, Lehnert, Martin, Hoffmeyer, Frank, Liebers, Verena, Van Gelder, Rainer, Udo Käfferlein, Heiko, Hartwig, Andrea, Pesch, Beate, Brüning, Thomas

Journal:

Journal of Toxicology and Environmental Health Part A

Année:

2016

Langue:

english

Fichier:

PDF, 1.23 MB

english, 2016

4

Integrating spatial, morphological, and textural information for improved cell type differentiation using Raman microscopy

Krauß, Sascha D., Yosef, Hesham K., Lechtonen, Tatjana, Jütte, Hendrik, Tannapfel, Andrea, Käfferlein, Heiko U., Brüning, Thomas, Roghmann, Florian, Noldus, Joachim, El-Mashtoly, Samir F., Gerwert, Kl

Journal:

Journal of Chemometrics

Année:

2018

Langue:

english

Fichier:

PDF, 4.97 MB

english, 2018

5

Carcinogenicity of some nitrobenzenes and other industrial chemicals

Van den Berg, M, Cattley, R, Cherrie, J W, Dorman, D C, Dunnick, J K, Gohlke, J M, Jinot, J, Käfferlein, H U, Kopylev, L, Matsumoto, M, Nomiyama, T, Ogawa, K, Perbellini, L, Sone, H, Grosse, Y, Guyton

Journal:

The Lancet Oncology

Année:

2018

Langue:

english

Fichier:

PDF, 57 KB

english, 2018

6

Decreased production of TNF and IL-6 in whole blood of CLL patients

E. Oahlke, R. Schlag, I. Langenmayer, M. Frankenberger, E. Käfferlein, T. Subkowski, B. Emmerich, H. W. L. Ziegler-Heitbrock

Journal:

American Journal of Hematology

Année:

1995

Langue:

english

Fichier:

PDF, 616 KB

english, 1995

7

Gas chromatographic method using electron-capture detection for the determination of musk xylene in human blood samples.: Biological monitoring of the general population

J Angerer, H.U Käfferlein

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Année:

1997

Langue:

english

Fichier:

PDF, 347 KB

english, 1997

8

Simultaneous determination of two human urinary metabolites of N,N-dimethylformamide using gas chromatography–thermionic sensitive detection with mass spectrometric confirmation

Heiko U Käfferlein, Jürgen Angerer

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Année:

1999

Langue:

english

Fichier:

PDF, 600 KB

english, 1999

9

DNA strand breaks in the lymphocytes of workers exposed to diisocyanates: indications of individual differences in susceptibility after low-dose and short-term exposure

B. Marczynski, R. Merget, T. Mensing, S. Rabstein, M. Kappler, A. Bracht, M. G. Haufs, H. U. Käfferlein, T. Brüning

Journal:

Archives of Toxicology

Année:

2005

Langue:

english

Fichier:

PDF, 341 KB

english, 2005

10

Assessment of micronuclei in lymphocytes from workers exposed to vapours and aerosols of bitumen

Peter Welge, Boleslaw Marczynski, Monika Raulf-Heimsoth, Anne Spickenheuer, Benjamin Kendzia, Evelyn Heinze, Jürgen Angerer, Heiko U. Käfferlein, Beate Pesch, Thomas Brüning

Journal:

Archives of Toxicology

Année:

2011

Langue:

english

Fichier:

PDF, 287 KB

english, 2011

11

N-methylcarbamoyl adducts at the N-terminal valine of globin in workers exposed to N,N-dimethylformamide

Jürgen Angerer, Thomas Göen, Axel Krämer, Heiko Udo Käfferlein

Journal:

Archives of Toxicology

Année:

1998

Langue:

english

Fichier:

PDF, 512 KB

english, 1998

12

Analysis of metabolites ofN,N-dimethylformamide in urine samples

H. U. Käfferlein, J. Mráz, C. Ferstl, J. Angerer

Journal:

International Archives of Occupational and Environmental Health

Année:

2004

Langue:

english

Fichier:

PDF, 235 KB

english, 2004

13

Biological monitoring of workers exposed toN,N-dimethylformamide in the synthetic fibre industry

H. U. Käfferlein, T. Göen, J. Müller, R. Wrbitzky, J. Angerer

Journal:

International Archives of Occupational and Environmental Health

Année:

2000

Langue:

english

Fichier:

PDF, 147 KB

english, 2000

14

Trends in the musk xylene concentrations in plasma samples from the general population from 1992/1993 to 1998 and the relevance of dermal uptake

Heiko U. Käfferlein, Jürgen Angerer

Journal:

International Archives of Occupational and Environmental Health

Année:

2001

Langue:

english

Fichier:

PDF, 136 KB

english, 2001

15

The Antibody MY4 Recognizes CD14 on Porcine Monocytes and Macrophages

H. W. L. ZIEGLER-HEITBROCK, B. APPL, E. KÄFFERLEIN, T. LÖFFLER, H. JAHN-HENNINGER, W. GUTENSOHN, J. R. NORES, K. MCCULLOUGH, B. PASSLICK, M. O. LABETA, J. IZBICKI

Journal:

Scandinavian Journal of Immunology

Année:

1994

Langue:

english

Fichier:

PDF, 2.30 MB

english, 1994

16

Quality of life in 1000 patients with early relapsing–remitting multiple sclerosis

N. Putzki, J. Fischer, K. Gottwald, G. Reifschneider, S. Ries, A. Siever, F. Hoffmann, W. Käfferlein, U. Kausch, M. Liedtke, J. Kirchmeier, S. Gmünd, A. Richter, P. Schicklmaier, G. Niemczyk, C. Werns

Journal:

European Journal of Neurology

Année:

2009

Langue:

english

Fichier:

PDF, 238 KB

english, 2009

17

DNA adduct formation of benzo[a]pyrene in white blood cells of workers exposed to polycyclic aromatic hydrocarbons

Thomas Mensing, Boleslaw Marczynski, Beate Engelhardt, Michael Wilhelm, Ralf Preuss, Martin Kappler, Jürgen Angerer, Heiko U. Käfferlein, Michael Scherenberg, Albrecht Seidel, Thomas Brüning

Journal:

International Journal of Hygiene and Environmental Health

Année:

2005

Langue:

english

Fichier:

PDF, 236 KB

english, 2005

18

Assessment of micronucleus frequencies in lymphocytes of workers exposed to fumes of bitumen—Results of the human bitumen study

P. Welge, B. Marczynski, M. Raulf-Heimsoth, A. Spickenheuer, B. Kendzia, E. Heinze, A. Erkes, M. Hagnia, H.U. Käfferlein, B. Pesch, T. Brüning

Journal:

Toxicology Letters

Année:

2010

Langue:

english

Fichier:

PDF, 71 KB

english, 2010

19

Phthalate exposure during cold plastisol application—a human biomonitoring study

Holger Martin Koch, Andreas Haller, Tobias Weiß, Heiko-Udo Käfferlein, Joachim Stork, Thomas Brüning

Journal:

Toxicology Letters

Année:

2012

Langue:

english

Fichier:

PDF, 481 KB

english, 2012

20

Internal exposure to carcinogenic polycyclic aromatic hydrocarbons and DNA damage: a null result in brief

Heiko U. Käfferlein, Boleslaw Marczynski, Patrice Simon, Jürgen Angerer, Hans-Peter Rihs, Michael Wilhelm, Kurt Straif, Beate Pesch, Thomas Brüning

Journal:

Archives of Toxicology

Année:

2012

Langue:

english

Fichier:

PDF, 359 KB

english, 2012

21

Partition of metals in the maternal/fetal unit and lead-associated decreases of fetal iron and manganese: an observational biomonitoring approach

Ricarda S. Kopp, Michael Kumbartski, Volker Harth, Thomas Brüning, Heiko U. Käfferlein

Journal:

Archives of Toxicology

Année:

2012

Langue:

english

Fichier:

PDF, 380 KB

english, 2012

22

PAH metabolites in urine and genotoxic effects in white blood cells of mastic asphalt workers exposed to fumes and aerosols of bitumen in a cross-shift study

B. Marczynski, M. Raulf-Heimsoth, R. Preuss, M. Kappler, H.U. Käfferlein, K. Schott, B. Pesch, T. Mensing, A. Spickenheuer, J. Angerer, T. Brüning

Journal:

Toxicology Letters

Année:

2006

Langue:

english

Fichier:

PDF, 87 KB

english, 2006

23

Risk assessment of workers exposed to fumes of bitumen: genotoxic effects and urinary metabolites of naphthalene, phenanthrene, and pyrene

Boleslaw Marczynski, Monika Raulf-Heimsoth, Heiko Udo Käfferlein, Katrin Förster, Anne Spickenheuer, Beate Pesch, Dietmar Breuer, Jürgen Angerer, Peter Welge, Rainer Bramer, Jens-Uwe Hahn, Thomas Mens

Journal:

Toxicology Letters

Année:

2007

Langue:

english

Fichier:

PDF, 96 KB

english, 2007

24

DNA strand breaks detected by Comet assay in sputum leucocytes of workers exposed to fumes of bitumen: A pilot study

Boleslaw Marczynski, Monika Raulf-Heimsoth, Benjamin Kendzia, Anne Spickenheuer, Brigitta Vosshans, Gerda Borowitzki, Eun-Hyun Lee, Heiko Udo Käfferlein, Beate Pesch, Thomas Brüning

Journal:

Toxicology Letters

Année:

2009

Langue:

english

Fichier:

PDF, 75 KB

english, 2009

25

Analyses in human urothelial cells identify methylation of miR-152, miR-200b and miR-10a genes as candidate bladder cancer biomarkers

Köhler, Christina U., Bryk, Oleksandr, Meier, Swetlana, Lang, Kerstin, Rozynek, Peter, Brüning, Thomas, Käfferlein, Heiko U.

Journal:

Biochemical and Biophysical Research Communications

Année:

2013

Langue:

english

Fichier:

PDF, 698 KB

english, 2013

26

Quantification of Four Major Metabolites of Embryotoxic N -Methyl- and N -Ethyl-2-pyrrolidone in Human Urine by Cooled-Injection Gas Chromatography and Isotope Dilution Mass Spectrometry

Schindler, Birgit K., Koslitz, Stephan, Meier, Swetlana, Belov, Vladimir N., Koch, Holger M., Weiss, Tobias, Brüning, Thomas, Käfferlein, Heiko U.

Journal:

Analytical Chemistry

Année:

2012

Langue:

english

Fichier:

PDF, 856 KB

english, 2012

27

N-Acetyl-4-aminophenol (paracetamol), N-acetyl-2-aminophenol and acetanilide in urine samples from the general population, individuals exposed to aniline and paracetamol users

Dierkes, Georg, Weiss, Tobias, Modick, Hendrik, Käfferlein, Heiko Udo, Brüning, Thomas, Koch, Holger M.

Journal:

International Journal of Hygiene and Environmental Health

Année:

2014

Langue:

english

Fichier:

PDF, 558 KB

english, 2014

28

Miniaturization of cytotoxicity tests for concentration range-finding studies prior to conducting the pH 6.7 Syrian hamster embryo cell-transformation assay

Plöttner, Sabine, Käfferlein, Heiko U., Brüning, Thomas

Journal:

Mutation Research/Genetic Toxicology and Environmental Mutagenesis

Année:

2013

Langue:

english

Fichier:

PDF, 1.46 MB

english, 2013

29

Levels and predictors of airborne and internal exposure to chromium and nickel among welders—Results of the WELDOX study

Weiss, Tobias, Pesch, Beate, Lotz, Anne, Gutwinski, Eleonore, Van Gelder, Rainer, Punkenburg, Ewald, Kendzia, Benjamin, Gawrych, Katarzyna, Lehnert, Martin, Heinze, Evelyn, Hartwig, Andrea, Käfferlein

Journal:

International Journal of Hygiene and Environmental Health

Année:

2013

Langue:

english

Fichier:

PDF, 556 KB

english, 2013

30

Metabolism and elimination ofN-ethyl-2-pyrrolidone (NEP) in human males after oral dosage

Koch, H. M., Bader, M., Weiss, T., Koslitz, S., Schütze, A., Käfferlein, H.-U., Brüning, T.

Journal:

Archives of Toxicology

Année:

2014

Langue:

english

Fichier:

PDF, 394 KB

english, 2014

31

Human exposure to airborne aniline and formation of methemoglobin: a contribution to occupational exposure limits

Käfferlein, Heiko Udo, Broding, Horst Christoph, Bünger, Jürgen, Jettkant, Birger, Koslitz, Stephan, Lehnert, Martin, Marek, Eike Maximilian, Blaszkewicz, Meinolf, Monsé, Christian, Weiss, Tobias, Brü

Journal:

Archives of Toxicology

Année:

2014

Langue:

english

Fichier:

PDF, 1.75 MB

english, 2014

32

Musk Xylene: Analysis, Occurrence, Kinetics, and Toxicology

Käfferlein, Heiko Udo, Göen, Thomas, Angerer, Jürgen

Journal:

Critical Reviews in Toxicology

Année:

1998

Langue:

english

Fichier:

PDF, 258 KB

english, 1998

33

437: Identification of a specific and sensitive urinary DNA hypermethylation signature for bladder cancer diagnosis

Köhler, C.U., Ahrens, M., Behrens, T., Eisenacher, M., Braun, K., Jöckel, K.H., Erbel, R., Tannapfel, A., Brüning, T., Käfferlein, H.U.

Journal:

European Journal of Cancer

Année:

2014

Langue:

english

Fichier:

PDF, 69 KB

english, 2014

34

N -Methylcarbamoylated Valine of Hemoglobin in Humans after Exposure to N,N -Dimethylformamide: Evidence for the Formation of Methyl Isocyanate?

Käfferlein, Heiko Udo, Angerer, Jürgen

Journal:

Chemical Research in Toxicology

Année:

2001

Langue:

english

Fichier:

PDF, 102 KB

english, 2001

35

Determination of N-acetyl-S-(N-methylcarbamoyl)cysteine (AMCC) in the general population using gas chromatography-mass spectrometry

Käfferlein, Heiko U., Angerer, Jürgen

Journal:

Journal of Environmental Monitoring

Année:

1999

Langue:

english

Fichier:

PDF, 128 KB

english, 1999

36

P101 BetaIGH3 in urine as biomarker for high grade bladder cancer diagnostics

Lang, K., Robens, S., Braun, K., Sommerer, F., Behrens, T., Noldus, J., Tannapfel, A., Jöckel, K-H., Erbel, R., Brüning, T., Käfferlein, H.U.

Journal:

European Urology Supplements

Année:

2014

Langue:

english

Fichier:

PDF, 61 KB

english, 2014

37

Biomarkers of polycyclic aromatic hydrocarbon exposure in European coke oven workers

Talaska, Glenn, Thoroman, Jeff, Schuman, Brenda, Käfferlein, Heiko Udo

Journal:

Toxicology Letters

Année:

2014

Langue:

english

Fichier:

PDF, 803 KB

english, 2014

38

Biomonitoring of N-ethyl-2-pyrrolidone in automobile varnishers

Koslitz, Stephan, Meier, Swetlana, Schindler, Birgit Karin, Weiß, Tobias, Koch, Holger Martin, Brüning, Thomas, Käfferlein, Heiko Udo

Journal:

Toxicology Letters

Année:

2014

Langue:

english

Fichier:

PDF, 480 KB

english, 2014

39

Levels and predictors of airborne and internal exposure to manganese and iron among welders

Pesch, Beate, Weiss, Tobias, Kendzia, Benjamin, Henry, Jana, Lehnert, Martin, Lotz, Anne, Heinze, Evelyn, Käfferlein, Heiko Udo, Van Gelder, Rainer, Berges, Markus, Hahn, Jens-Uwe, Mattenklott, Markus

Journal:

Journal of Exposure Science and Environmental Epidemiology

Année:

2012

Langue:

english

Fichier:

PDF, 428 KB

english, 2012

40

Oxidatively damaged guanosine in white blood cells and in urine of welders: associations with exposure to welding fumes and body iron stores

Pesch, Beate, Lotz, Anne, Koch, Holger M., Marczynski, Boleslaw, Casjens, Swaantje, Käfferlein, Heiko U., Welge, Peter, Lehnert, Martin, Heinze, Evelyn, Van Gelder, Rainer, Hahn, Jens-Uwe, Behrens, Th

Journal:

Archives of Toxicology

Année:

2015

Langue:

english

Fichier:

PDF, 464 KB

english, 2015

41

Dermal Uptake and Excretion of 4,4'-Methylenedianiline during Rotor Blade Production in Helicopter Industry--An Intervention Study

Weiss, T., Schuster, H., Muller, J., Schaller, K.-H., Drexler, H., Angerer, J., Kafferlein, H. U.

Journal:

The Annals of Occupational Hygiene

Année:

2011

Langue:

english

Fichier:

PDF, 223 KB

english, 2011

42

Albumin and hemoglobin adducts of benzo[ a ]pyrene in humans—Analytical methods, exposure assessment, and recommendations for future directions

Käfferlein, Heiko U., Marczynski, Boleslaw, Mensing, Thomas, Brüning, Thomas

Journal:

Critical Reviews in Toxicology

Année:

2010

Langue:

english

Fichier:

PDF, 1.02 MB

english, 2010

43

Dose-Response Modeling of Occupational Exposure to Polycyclic Aromatic Hydrocarbons with Biomarkers of Exposure and Effect

Pesch, B., Kappler, M., Straif, K., Marczynski, B., Preuss, R., Rossbach, B., Rihs, H.-P., Weiss, T., Rabstein, S., Pierl, C., Scherenberg, M., Adams, A., Kafferlein, H. U., Angerer, J., Wilhelm, M.,

Journal:

Cancer Epidemiology Biomarkers & Prevention

Année:

2007

Langue:

english

Fichier:

PDF, 306 KB

english, 2007

44

Detection of DNA strand breaks by comet assay in sputum leucocytes of bitumen-exposed workers: A pilot study

Marczynski, B., Raulf-Heimsoth, M., Pesch, B., Kendzia, B., Kafferlein, H., Vosshans, B., Borowitzki, G., Lee, E.-H., Bramer, R., Bruning, T.

Journal:

Human & Experimental Toxicology

Année:

2010

Langue:

english

Fichier:

PDF, 237 KB

english, 2010

45

The use of biomarkers of exposure of N,N-dimethylformamide in health risk assessment and occupational hygiene in the polyacrylic fibre industry

Kafferlein, H U

Journal:

Occupational and Environmental Medicine

Année:

2005

Langue:

english

Fichier:

PDF, 152 KB

english, 2005

46

Biomonitoring of Exposure to N-Methyl-2-Pyrrolidone in Workers of the Automobile Industry

Meier, S., Schindler, B. K., Koslitz, S., Koch, H. M., Weiss, T., Kafferlein, H. U., Bruning, T.

Journal:

The Annals of Occupational Hygiene

Année:

2013

Langue:

english

Fichier:

PDF, 2.04 MB

english, 2013

47

Ambient and Biological Monitoring of Exposure and Genotoxic Effects in Mastic Asphalt Workers Exposed to Fumes of Bitumen

Marczynski, Boleslaw, Raulf-Heimsoth, Monika, Spickenheuer, Anne, Mensing, Thomas, Welge, Peter, Förster, Katrin, Angerer, Jürgen, Pesch, Beate, Bramer, Rainer, Käfferlein, Heiko U., Breuer, Dietmar,

Journal:

Journal of Occupational and Environmental Hygiene

Année:

2007

Langue:

english

Fichier:

PDF, 111 KB

english, 2007

48

Human metabolism and excretion kinetics of aniline after a single oral dose

Modick, Hendrik, Weiss, Tobias, Dierkes, Georg, Koslitz, Stephan, Käfferlein, Heiko Udo, Brüning, Thomas, Koch, Holger Martin

Journal:

Archives of Toxicology

Année:

2016

Langue:

english

Fichier:

PDF, 729 KB

english, 2016

49

Genotoxic and cytotoxic activity of host defense peptides against human soft tissue sarcoma in an in vitro model

Steinstraesser, Lars, Hauk, Jennifer, Al-Benna, Sammy, Langer, Stefan, Ring, Andrej, Kesting, Marco, Sudhoff, Holger, Becerikli, Mustafa, Käfferlein, Heiko, Jacobsen, Frank

Journal:

Drug and Chemical Toxicology

Année:

2012

Langue:

english

Fichier:

PDF, 779 KB

english, 2012

50

424 CXCL16 and betaIGH3/TGFBI in urine as biomarkers for high-grade bladder cancer diagnostics

Lang, K., Robens, S., Braun, K., Tam, Y.C., Behrens, T., Noldus, J., Tannapfel, A., Brüning, T., Käfferlein, H.

Journal:

European Journal of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 62 KB

english, 2015